1-Phenyl-3-Hydroxy-1,2,4- Triazole
Benzoxolol industrial product is light yellow crystal, m.p. 284-286 ℃, soluble in dimethylformamide, slightly soluble in water.
Used as an intermediate in the pesticide triazophos.
1-Phenyl-3-Hydroxy-1,2,4-Triazole is a heterocyclic compound with applications in pharmaceuticals, agrochemicals, and specialty chemicals. It is valued for its reactive functional groups and stability under various conditions.
Chemical Characteristics
| Melting point | 277-280 |
| density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 9.13±0.20(Predicted) |
| CAS DataBase Reference | 4231-68-9(CAS DataBase Reference) |
Applications
Pharmaceuticals:
Intermediate in the synthesis of drugs with antifungal, antibacterial, or antiviral properties.
Used in developing active pharmaceutical ingredients (APIs).
Agrochemicals:
Precursor in the production of fungicides and herbicides.
Enhances the efficacy of crop protection formulations.
Specialty Chemicals:
Employed in the synthesis of fine chemicals and performance materials.
Acts as a building block in advanced organic synthesis.
Advantages
High chemical reactivity for versatile applications.
Stable crystalline form ensures ease of handling and storage.
Suitable for use in a variety of industrial processes.
Safety and Handling
Protective Measures:
Use gloves, goggles, and protective clothing while handling.
Operate in a well-ventilated area or under a fume hood.
Storage:
Store in a cool, dry place, away from direct sunlight and moisture.
Keep container tightly sealed to prevent contamination.
Hazards:
Inhalation: May irritate the respiratory system.
Skin Contact: Can cause irritation upon prolonged exposure.
Eye Contact: Risk of severe irritation.
Ingestion: Harmful if swallowed; may cause gastrointestinal distress.
First Aid Measures:
Inhalation: Move to fresh air; seek medical attention if symptoms persist.
Skin Contact: Wash thoroughly with soap and water.
Eye Contact: Flush with water for at least 15 minutes; consult a doctor.
Ingestion: Rinse mouth; do not induce vomiting; seek immediate medical help.
Conclusion
1-Phenyl-3-Hydroxy-1,2,4-Triazole is a versatile chemical compound with broad applications in pharmaceuticals, agrochemicals, and specialty chemicals. Its high purity, stability, and reactive nature make it a valuable choice for industrial and research purposes. Proper handling and storage are essential to maintain its integrity and ensure safety.
FAQ
1. What is the primary use of 1-Phenyl-3-Hydroxy-1,2,4-Triazole?
It is widely used as an intermediate in pharmaceuticals and agrochemicals.
2. Is it water-soluble?
It is slightly soluble in water but dissolves readily in organic solvents.
3. How should it be stored?
Store in a cool, dry, and well-ventilated area, away from moisture and sunlight.
4. Is it hazardous?
Yes, it may cause irritation or harm upon contact or ingestion. Handle with care.
5. Can it degrade under certain conditions?
Yes, it may degrade in strong acidic or basic environments.
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