2,6-Xylidine

2,6-Dimethylaniline is slightly yellow liquid, b.p.216～217℃, m.p.10～12℃, n20D 1.5590, relative density 0.973, insoluble in water, soluble in alcohol, ether, soluble in hydrochloric acid.

2, 6-dimethylaniline is an intermediate in pesticide, medicine and veterinary drugs. In the pesticide industry, it is used in the production of highly effective fungicides metalaxyl, furaxyl, furamide, mefuramide, fenaxyl, virulent alum and highly effective and low toxic selective herbicides isobutachlor, Tredo (dimethylachlor) and imidazolamide, etc. In the pharmaceutical industry, it is used in the production of anesthetic drugs lidocaine hydrochloride, bupivacaine hydrochloride, ventricular ancaine hydrochloride, tocaronium, dujuan and other drugs. In addition, it is also a raw material for the production of the veterinary drug pinoline.

2,6-Xylidine is an aromatic amine used primarily as an intermediate in the production of dyes, agrochemicals, and pharmaceuticals. Its chemical properties make it a valuable component in industrial synthesis.

Chemical Characteristics

Applications

1. Dye Manufacturing:

   • Serves as a precursor in the synthesis of various dyes.

   • Provides chromophoric properties essential for vivid color production.

2. Agrochemical Synthesis:

   • Used in the production of herbicides, fungicides, and insecticides.

3. Pharmaceutical Industry:

   • Acts as an intermediate in the synthesis of active pharmaceutical ingredients (APIs).

   • Key component in the production of certain anesthetics and antihistamines.

4. Specialty Chemicals:

   • Integral in the manufacture of resins and polymers.

   • Contributes to the production of performance-enhancing materials.

Advantages

• High purity ensures reliability in industrial processes.

• Versatile reactivity for diverse chemical synthesis pathways.

• Stable under proper storage conditions.

Safety and Handling

• Protective Measures:

  • Use gloves, safety goggles, and protective clothing during handling.

  • Ensure proper ventilation or operate in a fume hood.

• Storage:

  • Store in a cool, dry, and well-ventilated area, away from oxidizing agents and direct sunlight.

  • Keep the container tightly sealed to prevent contamination.

• Hazards:

  • Inhalation: Can cause respiratory irritation.

  • Skin Contact: May cause irritation or sensitization.

  • Eye Contact: Risk of severe irritation.

  • Ingestion: Harmful if swallowed; may cause systemic toxicity.

• First Aid Measures:

  • Inhalation: Move to fresh air; seek medical attention if symptoms persist.

  • Skin Contact: Wash thoroughly with soap and water.

  • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; consult a doctor.

  • Ingestion: Do not induce vomiting; seek immediate medical attention.

Conclusion

2,6-Xylidine is a versatile and essential intermediate in the production of dyes, agrochemicals, and pharmaceuticals. Its stability and reactivity make it a valuable choice for industrial applications. Proper handling and storage are critical to ensuring safety and maintaining its quality.

FAQ

1. What is the primary use of 2,6-Xylidine?
It is primarily used as an intermediate in the production of dyes, agrochemicals, and pharmaceuticals.

2. Is it water-soluble?
It is slightly soluble in water but highly soluble in organic solvents.

3. What are the storage recommendations?
Store in a cool, dry, and well-ventilated area, away from oxidizing agents.

4. Is it hazardous?
Yes, it can cause irritation or harm upon contact, inhalation, or ingestion. Handle with care.

5. Can it oxidize?
Yes, it may oxidize upon prolonged exposure to air, which can affect its stability.