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Cas No. 133-06-2
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Detail

Clotrimazole industrial product is a colorless to beige amorphous solid with a pungent odor. Pure product is colorless crystalline solid, melting point 178℃(tech.,175~178℃)


Used as a protective fungicide, foliar spraying or seed dressing can be used, safe for crops, no harm, but also has the role of stimulating plant growth.


Captan is a non-systemic, broad-spectrum fungicide widely used in agriculture to control fungal diseases on fruits, vegetables, and ornamental plants. Its multi-site mode of action makes it effective for disease prevention and resistance management.


Key Features

  1. Chemical Class: Phthalimide fungicide.

  2. Mode of Action: Multi-site inhibitor, disrupting multiple biochemical processes in fungi.

  3. Formulations: Available as wettable powders (WP), dusts, and liquid concentrates.

  4. Contact Fungicide: Remains on the plant surface, forming a protective barrier.


Applications

Crops

  • Fruits: Apples, pears, peaches, strawberries, and grapes.

  • Vegetables: Tomatoes, cucumbers, and potatoes.

  • Ornamentals: Roses and other flowering plants.

Target Diseases

  • Scab (Venturia spp.).

  • Botrytis rot (Botrytis cinerea).

  • Anthracnose (Colletotrichum spp.).

  • Leaf spots (Cercospora spp., Alternaria spp.).

  • Powdery mildew (Oidium spp.).


Mode of Action

Captan works by disrupting multiple enzymatic processes in fungi, effectively inhibiting spore germination and mycelial growth. Its multi-site activity reduces the risk of resistance development.


Advantages

  1. Broad-Spectrum Activity: Effective against a wide range of fungal pathogens.

  2. Resistance Management: Multi-site mode of action limits resistance buildup.

  3. Crop Safety: Low risk of phytotoxicity when used as directed.

  4. Compatibility: Can be tank-mixed with other pesticides for integrated pest management (IPM).


Usage Guidelines

  1. Application Timing: Apply preventively before fungal spores germinate.

  2. Dosage: Follow label recommendations for specific crops and diseases.

  3. Coverage: Ensure thorough and even coverage of plant surfaces.

  4. Reapplication Interval: Typically 7–14 days, depending on disease pressure and weather conditions.


Safety and Environmental Considerations

Handling and Storage

  • Protective Measures: Wear gloves, goggles, and protective clothing during handling.

  • Storage: Store in a cool, dry, and well-ventilated area, away from food and feed.

Environmental Impact

  • Aquatic Toxicity: Avoid runoff into water bodies to protect aquatic organisms.

  • Soil Persistence: Low to moderate persistence; follow recommended application rates.

Human Health Risks

  • Toxicity: Slightly toxic if ingested or inhaled; may cause skin and eye irritation.

  • First Aid:

    • Skin Contact: Wash thoroughly with soap and water.

    • Eye Contact: Rinse immediately with plenty of water for at least 15 minutes.

    • Inhalation: Move to fresh air and seek medical attention if symptoms occur.



Limitations

  1. Non-Systemic Action: Requires regular applications for continued protection.

  2. Rainfastness: Effectiveness may be reduced by heavy rainfall; reapplication may be needed.

  3. Residue Management: Observe pre-harvest intervals to minimize residues on crops.


Conclusion

Captan is a reliable fungicide for managing a variety of fungal diseases in agricultural and ornamental plants. Its multi-site action, combined with preventive properties, makes it a cornerstone in sustainable disease management programs. Proper application ensures healthy crops and high yields.


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