Cyproconazole

Colorless crystal, melting point 106~109℃, boiling point> 250℃, vapor pressure 0.03470mPa at 20℃, density 1.259, solubility 1.4g/kg in water at 25℃.

Epoxiconazole is a triazole agricultural fungicide, the mechanism of action is to inhibit the demethylation of sterols, with preventive and therapeutic effects, has been widely used in the field of pesticides , cereal crops, coffee, sugar beets, and fruit trees on the powdery mildew, rust, caecilomycetes, rostrosporidium, chitinosporium, and blackstar fungus on the fungus are effective.

Cyproconazole is a systemic triazole fungicide used for the prevention and treatment of fungal diseases in various crops. It inhibits fungal growth by targeting sterol biosynthesis, essential for cell membrane formation in fungi.

Key Features

1. Chemical Class: Triazole fungicide.

2. Mode of Action: Demethylation inhibitor (DMI), disrupting sterol production in fungal cell membranes.

3. Formulations: Available as emulsifiable concentrates (EC) and suspension concentrates (SC).

4. Systemic Activity: Rapidly absorbed by plants and translocated to provide protective and curative effects.

Applications

Crops

• Cereals: Wheat, barley, and oats.

• Oilseeds: Soybeans, rapeseed, and sunflower.

• Fruits: Bananas, citrus, and apples.

• Vegetables: Tomatoes and cucumbers.

Target Diseases

• Leaf rusts (Puccinia spp.).

• Powdery mildew (Erysiphe spp.).

• Septoria leaf blotch (Septoria tritici).

• Net blotch (Pyrenophora teres).

• Anthracnose (Colletotrichum spp.).

Mode of Action

Cyproconazole inhibits the enzyme C14-demethylase, a critical step in ergosterol biosynthesis in fungi. This disruption weakens the fungal cell membrane, preventing growth and reproduction.

Advantages

1. Broad-Spectrum Control: Effective against multiple fungal pathogens.

2. Systemic Movement: Ensures even distribution within plant tissues.

3. Curative and Protective Action: Offers flexibility in application timing.

4. Resistance Management: Often used in combination with fungicides of different modes of action.

Usage Guidelines

1. Application Timing: Best applied at early disease onset or preventively.

2. Dosage: Follow specific recommendations for each crop and disease.

3. Reapplication Interval: Typically 14–21 days, depending on disease pressure.

4. Mixing: Ensure thorough mixing for uniform application.

Safety and Environmental Considerations

Handling and Storage

• Protective Measures: Use gloves, goggles, and protective clothing during handling.

• Storage: Store in a cool, dry place, away from food and animal feed.

Environmental Impact

• Aquatic Toxicity: Avoid contamination of water sources due to potential harm to aquatic life.

• Soil Persistence: Moderately persistent; follow recommended application rates to minimize environmental impact.

Human Health Risks

• Toxicity: Low acute toxicity but may cause irritation upon prolonged exposure.

• First Aid:

  • Skin Contact: Wash thoroughly with soap and water.

  • Eye Contact: Rinse immediately with plenty of water.

  • Inhalation: Move to fresh air and seek medical attention if symptoms occur.

  
  

Limitations

1. Resistance Risk: Overuse may lead to resistance development; rotate with fungicides of different modes of action.

2. Rainfastness: Reapplication may be necessary after heavy rain.

3. Residue Management: Adhere to pre-harvest intervals to minimize residues.

Conclusion

Cyproconazole is a versatile and effective fungicide for managing a wide range of fungal diseases in crops. Its systemic activity, combined with curative and protective properties, makes it a valuable component in integrated disease management strategies. Proper use ensures sustainable crop protection and optimal yields.