Metalaxyl-M

It is light brown, viscous, transparent liquid. Melting point: -38.7℃ (pure product). Vapor pressure: 3.3×10-3 Pa (25℃ , pure product). Solubility: in water: 26 g/L (25℃ , pure product); in organic solvent: 59 g/L (25℃ , hexane), miscible with acetone, ethyl acetate, methanol, dichloromethane, toluene, and n-octanol.

It is highly effective for diseases of vegetables, fruit trees, tobacco, oilseeds, cotton, grain and other crops caused by downy mildew, phytophthora, and rot fungus.

Metalaxyl-M, also known as Mefenoxam, is a systemic fungicide widely used to control diseases caused by oomycetes, such as Pythium, Phytophthora, and Peronospora species. It is a more active isomer of Metalaxyl, offering enhanced effectiveness at lower application rates. This fungicide is extensively applied in agriculture to protect crops, seeds, and soil from destructive fungal infections.

Key Features

1. Systemic Protection: Penetrates plant tissues to provide internal protection.

2. Target-Specific Action: Effective against oomycete fungi while sparing beneficial organisms.

3. Seed Treatment: Commonly used to coat seeds for early-stage disease prevention.

4. Enhanced Efficacy: Higher potency compared to Metalaxyl, allowing for reduced application rates.

Applications

Crops Treated

• Vegetables: Tomatoes, potatoes, cucumbers, and peppers.

• Fruits: Grapes, citrus, and avocados.

• Field Crops: Corn, soybeans, and wheat.

• Ornamentals: Roses and bedding plants.

Diseases Controlled

• Pythium damping-off

• Phytophthora root rot

• Downy mildew

• Late blight (Phytophthora infestans)

Mechanism of Action

Metalaxyl-M inhibits RNA polymerase activity in the target fungi, disrupting protein synthesis and halting fungal growth. Its systemic nature allows it to be absorbed by roots, stems, and leaves, providing both preventive and curative protection against infections.

Advantages

1. Broad-Spectrum Control: Effective against a wide range of oomycete diseases.

2. Systemic Activity: Protects all parts of the plant, including new growth.

3. Seed and Soil Application: Versatile usage for early-stage protection.

4. Reduced Dosage: Higher potency allows for lower application rates, minimizing environmental impact.

Safety and Environmental Considerations

Handling and Storage

• Use personal protective equipment (PPE), including gloves, goggles, and masks, during handling and application.

• Store in a cool, dry, and well-ventilated area, away from food, feed, and water.

Environmental Impact

• Aquatic Toxicity: Avoid runoff into water bodies to protect aquatic ecosystems.

• Soil Mobility: Metalaxyl-M can leach into soil; careful application is required.

• Non-Target Organisms: Minimal impact on beneficial fungi and insects when used as directed.

Regulatory Compliance

• Approved for use in many countries with specific guidelines. Always adhere to local regulations for safe and effective use.

Limitations

• Resistance Development: Overuse may lead to resistance in target pathogens.

• Limited Spectrum: Ineffective against non-oomycete fungi.

• Environmental Sensitivity: Requires careful application to prevent contamination.

Conclusion

Metalaxyl-M is a highly effective fungicide for managing oomycete diseases in various crops. Its systemic activity, broad-spectrum control, and reduced environmental footprint make it a preferred choice for disease management in agriculture. Adherence to application guidelines and integrated pest management practices ensures sustainable and effective use.