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Cas No. 2097691-58-0
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Detail

Oligopeptide-1 is a synthetic peptide containing Glycine (Gly), Histidine (Histidine), Lysine (Lysine) (Lys) three amino acids, the sequence is GHK.

1. Skin firmness, improve elasticity;

2. Improve skin density and toughness;

3. Reduce fine and deep lines;


Oligopeptide-1, also known as Epidermal Growth Factor (EGF), is a bioactive peptide that plays a crucial role in skin regeneration and repair. It is composed of a short chain of amino acids and is naturally found in human skin, where it stimulates cell growth and promotes tissue regeneration. Oligopeptide-1 is widely used in skincare for its rejuvenating, healing, and anti-aging properties.


Key Features

  • Skin Regeneration: Stimulates the growth and renewal of skin cells, promoting faster healing and improved skin texture.

  • Collagen Production: Enhances collagen synthesis, improving skin elasticity and reducing the appearance of fine lines and wrinkles.

  • Wound Healing: Accelerates the healing process of minor cuts, burns, and other skin injuries.

  • Moisturization: Supports the skin’s natural barrier, helping to retain moisture and improve hydration.

  • Anti-Aging: Reduces the visible signs of aging by encouraging the production of healthy, youthful skin cells.


Applications

Skincare

  • Anti-Aging Products: Oligopeptide-1 is a key ingredient in serums, creams, and masks aimed at reducing wrinkles and improving skin firmness.

  • Wound Healing: Found in formulations designed to promote healing and recovery for damaged or compromised skin.

  • Hydrating Treatments: Helps improve skin hydration and moisture retention, leaving the skin soft and plump.

  • Brightening Products: Can help even out skin tone and reduce hyperpigmentation by promoting healthy skin regeneration.

Medical and Dermatological Uses

  • Post-Procedure Care: Used in products designed to soothe and accelerate healing after dermatological treatments like laser resurfacing, chemical peels, or microdermabrasion.

  • Scarring Prevention: Helps reduce the formation of scars by promoting faster tissue regeneration.


Mechanism of Action

Oligopeptide-1 works by binding to specific receptors on skin cells, stimulating cell division and the production of collagen and elastin. This process enhances skin regeneration and repair, helping to maintain a youthful appearance. It also accelerates the healing of damaged skin by promoting the production of new skin cells.


Considerations

  • Concentration: Typically used in concentrations of 0.01% to 0.1% in skincare formulations.

  • Compatibility: Works well with other active ingredients such as hyaluronic acid, peptides, and antioxidants.

  • Skin Type: Suitable for all skin types, including sensitive skin.

  • Patch Test: Recommended for first-time users to ensure compatibility.

  • Pregnancy and Breastfeeding: Generally considered safe for use during pregnancy and breastfeeding, but it’s always advisable to consult with a healthcare provider.


Conclusion

Oligopeptide-1 is a potent and versatile ingredient that supports skin regeneration, collagen production, and wound healing. Its ability to promote healthy skin cell turnover makes it an essential component in anti-aging, hydrating, and healing skincare products. Whether used in serums, creams, or post-procedure treatments, Oligopeptide-1 helps maintain youthful, radiant skin while accelerating recovery from skin damage.


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