What Is Cymoxanil and Why Is It Widely Used in Crop Protection?

2025-08-19 09:41

Technical Introduction

Cymoxanil is a systemic, locally systemic (translaminar) fungicide belonging to the cyanoacetamide-oxime chemical group. Unlike contact fungicides, Cymoxanil penetrates the leaf surface and moves into plant tissues, providing short-term protective, curative, and antisporulant activity.

Its primary mode of action is the inhibition of nucleic acid synthesis in fungal cells, which prevents pathogen development and spore germination. Because of its rapid uptake and short residual life, Cymoxanil is most effective when used in combination with contact fungicides such as mancozeb, copper oxychloride, or chlorothalonil, ensuring both immediate protection and extended persistence.

Applications

  • Potatoes & Tomatoes: Highly effective against late blight (Phytophthora infestans).

  • Grapes: Used to control downy mildew (Plasmopara viticola).

  • Vegetables (onion, lettuce, cucumbers, peppers): Protects against various downy mildews.

  • Sugar Beet & Other Crops: Used against foliar diseases caused by oomycetes.

  • Combination Products: Often formulated with fungicides like mancozeb, cymoxanil+mancozeb being one of the most common anti-blight solutions worldwide.

Advantages

  • Systemic & Translaminar Movement: Penetrates leaf tissues for inside-out protection.

  • Curative Effect: Can stop early infection within 24–48 hours of pathogen entry.

  • Anti-Sporulant Activity: Reduces spread by suppressing sporulation.

  • Fast Absorption: Quickly absorbed, limiting wash-off losses from rain.

  • Resistance Management: When combined with multi-site fungicides, reduces resistance risks.

Specifications (Typical Parameters)

ParameterDescriptionTypical Value
Chemical Name2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino)acetamideCymoxanil
Chemical FormulaMolecular compositionC₇H₁₀N₄O₃
Molecular Weight
~198.18 g/mol
AppearancePhysical stateOff-white crystalline solid
Formulation TypesWettable Powder (WP), Water-Dispersible Granules (WDG), Suspension Concentrate (SC)Common: 8% + partners, 50% WP
SolubilityIn water (25°C)~0.9 g/L (moderately soluble)
StabilityDegrades under sunlight & high temperaturesShort persistence (2–3 days)
Mode of ActionInhibits nucleic acid synthesisLocally systemic + curative

FAQ

Q1: Is Cymoxanil a long-lasting fungicide?
A: No, it has a short residual period (2–3 days), so it is almost always used in mixtures with longer-lasting fungicides like mancozeb or chlorothalonil.

Q2: Can Cymoxanil cure fungal infections after they appear?
A: Yes, it has curative properties within 1–2 days of infection, but it works best when applied early.

Q3: Is Cymoxanil effective alone?
A: It is rarely used alone due to its short persistence. Tank-mixing or ready-made combinations provide better control.

Q4: Which crops benefit most from Cymoxanil use?
A: Potatoes, tomatoes, grapes, cucumbers, onions, and other crops prone to late blight or downy mildew.

Q5: How does Cymoxanil help in resistance management?
A: Because it has a unique mode of action and is often combined with multi-site fungicides, it plays a key role in anti-resistance fungicide programs.

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