Phosalone: A Broad-Spectrum Organophosphate Insecticide and Acaricide

2025-08-21 10:07

Technical Introduction

Phosalone (chemical name: O,O-diethyl-O-[6-chloro-2-oxo-3-benzoxazolinyl] phosphorodithioate) is a broad-spectrum organophosphate insecticide and acaricide widely used in agriculture. It was developed in the 1960s and is known for its effectiveness against a wide range of insect pests and mites.

Its mode of action is typical of organophosphates:

  • Inhibits acetylcholinesterase (AChE), an essential enzyme in the nervous system of insects.

  • This causes accumulation of acetylcholine, leading to paralysis and eventual death of the pest.

Phosalone exhibits both contact and stomach action, with some residual activity on plant surfaces.


Applications

  • Agricultural Crops:

    • Widely used on cotton, fruits (apple, citrus, pear), vegetables, and cereals.

    • Controls chewing and sucking pests such as aphids, leafhoppers, thrips, caterpillars, beetles, and fruit borers.

    • Effective against mites (acaricidal action), making it dual-purpose.

  • Ornamentals:

    • Used in ornamental plant protection against mites and insect infestations.

  • Stored Products (in some regions):

    • Applied for control of stored grain pests, though less common compared to fumigants.

  • Veterinary / Public Health (limited):

    • Occasionally applied in ectoparasite control on animals, but mostly replaced by safer alternatives.


Advantages

  • Broad Spectrum: Effective against both insects and mites.

  • Dual Mode of Action: Contact and stomach poison, ensuring multiple routes of effectiveness.

  • Residual Activity: Provides long-lasting control compared to highly volatile OPs like dichlorvos.

  • Versatile Use: Applicable to field crops, orchards, vegetables, and ornamentals.

  • Cost-Effective: Relatively low production cost compared to newer insecticides.


Specifications (Typical Parameters)

ParameterDescriptionTypical Value
Chemical NameO,O-diethyl-O-[6-chloro-2-oxo-3-benzoxazolinyl] phosphorodithioatePhosalone
Chemical FormulaMolecular compositionC₁₂H₁₅ClNO₄PS₂
Molecular Weight
~367.8 g/mol
AppearancePhysical statePale yellow to brown liquid
Purity (TC)Technical concentrate≥ 95%
Mode of ActionAcetylcholinesterase inhibitorContact + stomach activity
Common FormulationsEC (emulsifiable concentrate), WP (wettable powder), dust35% EC, 50% WP
StabilityStable under normal conditions; degraded by strong alkaline mediaModerate persistence
ToxicityModerate (oral LD₅₀ in rats ~ 80–120 mg/kg)Hazardous if misused

FAQ

Q1: What crops benefit most from Phosalone?
A: It is widely applied on cotton, citrus, apple, pear, vegetable crops, and cereals, especially where both insect and mite infestations occur.

Q2: Is Phosalone systemic?
A: No, Phosalone is not systemic. It acts as a contact and stomach poison, with residual activity on treated surfaces.

Q3: How does it compare to other OP insecticides like Malathion or Chlorpyrifos?

  • Malathion: Safer but less potent, mainly for household and mosquito control.

  • Chlorpyrifos: Stronger residual soil insecticide, used for termites and root pests.

  • Phosalone: Balanced insect + mite control, primarily used in orchards and crops.

Q4: What precautions are required in handling?
A: As a moderately toxic organophosphate, applicators must wear PPE, avoid inhalation, and wash thoroughly after use. It should not be applied near water bodies due to fish toxicity.

Q5: Is Phosalone still registered worldwide?
A: Phosalone is restricted or banned in many countries due to environmental and toxicological concerns, but still used in some regions for crop protection where regulatory approval remains.

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