Hexaflumuron: An Effective Insect Growth Regulator (IGR)

2025-08-21 11:35

Technical Introduction

Hexaflumuron (IUPAC: 1-[3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl]-3-(difluoromethoxy)urea) is a benzoylurea insecticide that functions as an insect growth regulator (IGR). It primarily targets termites and other wood-destroying insects by inhibiting chitin synthesis, disrupting molting, and preventing normal exoskeleton development.

  • Mode of Action: Inhibits chitin biosynthesis, preventing proper exoskeleton formation, causing larval death.

  • Systemicity: Non-systemic; acts mainly via ingestion by larvae or termites.

  • Target Spectrum: Highly effective against termites, ants, and other wood-feeding insects.


Applications

  • Termite Control:

    • Used in soil treatment, baiting systems, and structural wood protection to control subterranean and drywood termites.

  • Urban Pest Management:

    • Applied to ant colonies and other nuisance insects in residential and commercial buildings.

  • Forestry & Wood Protection:

    • Protects timber, wooden structures, and furniture from termite damage.

  • Bait Formulations:

    • Commonly used in slow-acting bait systems, allowing insects to carry toxicant back to colonies.


Advantages

  • Colony-Level Control: Acts slowly, allowing termites to transfer the insecticide within the colony.

  • Low Mammalian Toxicity: Relatively safe for humans and pets when used according to label directions.

  • Target Specificity: Primarily affects insects undergoing molting, minimizing impact on non-target organisms.

  • Long-Term Protection: Provides lasting control of termite infestations.

  • Compatible with Bait Systems: Effective in both liquid and solid bait formulations.


Specifications (Typical Parameters)

ParameterDescriptionTypical Value
Chemical NameHexaflumuron
Chemical ClassBenzoylurea insecticide (IGR, IRAC 15)
Chemical FormulaC₁₇H₁₂Cl₂F₆N₂O₂
Molecular Weight~432.2 g/mol
AppearanceWhite to off-white crystalline powder
Purity (TC)≥ 95%
Common FormulationsGranules, wettable powders (WP), emulsifiable concentrates (EC), baits5%–10% bait, 10% WP
Mode of ActionChitin synthesis inhibitor; slow-acting
Target PestsTermites, ants, wood-feeding insects
Residual ActivityWeeks to months depending on application
ToxicityLow mammalian toxicity; safe for pets and humans under proper use

FAQ

Q1: How does Hexaflumuron kill termites?
A: It inhibits chitin synthesis, preventing proper exoskeleton formation during molting, leading to larval death and colony decline.

Q2: Is Hexaflumuron fast-acting?
A: No. It is slow-acting, allowing insects to transfer the insecticide within the colony, ensuring effective colony-level control.

Q3: Can it be used for general insect pests?
A: Its primary use is against termites and ants. It is less effective for general chewing or sucking pests.

Q4: Is Hexaflumuron safe for humans and pets?
A: Yes. It has low mammalian toxicity, but users should still follow label instructions for safe handling.

Q5: Can Hexaflumuron be used in bait systems?
A: Yes. It is highly effective in slow-acting bait formulations, allowing insects to carry it back to their colonies for systemic control.

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