Clodinafop-propargyl (IUPAC: (R)-2-[4-(5-chloro-3-fluoro-2-pyridyloxy)phenoxy]propionic acid prop-2-ynyl ester) is a post-emergence, selective systemic herbicide belonging to the aryloxyphenoxypropionate (FOP) group.
It is primarily used to control annual grass weeds in wheat and barley fields, without damaging the crops themselves.
Mode of Action: Inhibits the enzyme acetyl-CoA carboxylase (ACCase), which is essential for fatty acid biosynthesis in grasses. This disrupts cell membrane formation and kills susceptible grass weeds.
Selectivity: Kills grass weeds but is safe on broadleaf crops like wheat due to crop metabolism.
Systemicity: Absorbed by leaves, translocated to growing points.
Target Crops:
Wheat (main use)
Barley
Weeds Controlled:
Phalaris minor (littleseed canary grass)
Avena fatua (wild oats)
Lolium rigidum (ryegrass)
Setaria spp.
Echinochloa crus-galli (barnyard grass, partial control)
Usage Timing:
Applied post-emergence when weeds are at 2–4 leaf stage and the crop is well established.
Highly Selective: Effective on grass weeds without harming wheat.
Post-Emergence Application: Controls weeds after they have emerged, giving flexibility in weed management.
Low Application Rate: Highly active at low dosages.
Systemic Movement: Moves to the meristematic tissue, ensuring complete weed kill.
Alternative to Isoproturon: Very effective against isoproturon-resistant Phalaris minor in wheat.
Parameter | Description | Typical Value |
---|---|---|
Chemical Name | Clodinafop-propargyl | |
Chemical Class | Aryloxyphenoxypropionate (FOP) | |
Chemical Formula | C₁₇H₁₃ClFNO₄ | |
Molecular Weight | ~349.7 g/mol | |
Appearance | White to off-white crystalline solid | |
Purity (TC) | ≥ 95% | |
Common Formulations | 15% WP, 9% EC | |
Mode of Action | ACCase inhibitor | |
Target Weeds | Annual grasses in wheat | |
Application Rate | 60–80 g a.i./ha | |
Residual Activity | Moderate, controls weeds for 2–3 weeks | |
Toxicity | Oral LD₅₀ (rat) > 5,000 mg/kg (low toxicity) |
Q1: Which weeds are best controlled by Clodinafop-propargyl?
A: It is most effective against Phalaris minor, wild oats, and ryegrass in wheat crops.
Q2: Is it safe for broadleaf crops?
A: Yes, wheat and barley are tolerant due to rapid herbicide metabolism. However, it should not be used in oat crops, which are sensitive.
Q3: When should it be applied?
A: Apply post-emergence when weeds are at the 2–4 leaf stage for best results.
Q4: Can Clodinafop control broadleaf weeds?
A: No, it is specific to grass weeds. A tank mix with a broadleaf herbicide is often recommended.
Q5: Is there resistance to Clodinafop?
A: Yes, some grass weeds have developed resistance to ACCase inhibitors. Resistance management strategies (herbicide rotation, integrated weed management) are advised.