Isopropyl Alcohol (IPA), also known as 2-propanol or isopropanol, is a colorless, volatile, and flammable liquid with a sharp alcoholic odor. It is the simplest secondary alcohol, commonly used as a solvent, antiseptic, and cleaning agent.
Chemical Formula: C₃H₈O or C₃H₇OH
CAS Number: 67-63-0
Molecular Weight: 60.1 g/mol
Structure: Secondary alcohol (hydroxyl group attached to a secondary carbon)
Solubility: Miscible with water, ethanol, ether, chloroform, and most organic solvents
Key Functional Properties:
Excellent solvent for oils, resins, and gums
Fast evaporation with no residue
Antimicrobial activity against bacteria, fungi, and viruses
Good compatibility with water and other solvents
Used in hand sanitizers and surface disinfectants (typically 70% solutions for maximum efficacy).
Antiseptic for skin cleaning before injections.
Cleaning of medical instruments.
Cleans delicate components (circuit boards, connectors) without residue.
Removes flux residues after soldering.
Dissolves oils, dust, and fingerprints from glass and lenses.
Solvent in paints, inks, coatings, and adhesives.
Extraction agent in chemical processes.
De-icing fluid in aviation fuel systems.
Intermediate in the production of acetone, isopropyl acetate, and other chemicals.
Ingredient in window cleaners, detergents, and deodorants.
Used for cleaning electronics, mobile phones, and eyeglasses.
Added to personal care products like aftershaves and lotions.
Gasoline additive to prevent water condensation in fuel tanks.
Used as a de-icing agent for windshields.
Fast-drying & residue-free cleaning agent.
Broad-spectrum disinfectant against bacteria, fungi, and viruses.
Cost-effective solvent compared to ethanol.
Non-corrosive to most plastics, glass, and metals.
Highly versatile — used across medical, industrial, and household sectors.
Parameter | Specification Range |
---|---|
Chemical Name | Isopropyl Alcohol (IPA) |
CAS Number | 67-63-0 |
Molecular Weight | 60.1 g/mol |
Appearance | Clear, colorless liquid with alcoholic odor |
Purity (Common Grades) | 70%, 90%, 99% (anhydrous) |
Boiling Point | 82.6 °C |
Melting Point | –89 °C |
Flash Point | 11.7 °C (closed cup) |
Density | 0.785 g/cm³ at 20 °C |
Solubility | Miscible with water and most organics |
Evaporation Rate | Fast, leaves no residue |
Flammable: Keep away from open flames, sparks, and heat sources.
Health Hazards:
Inhalation → dizziness, headache, respiratory irritation.
Skin → drying effect, irritation with prolonged exposure.
Ingestion → toxic, may cause nausea and central nervous system depression.
Handling Precautions:
Use in well-ventilated areas.
Store in tightly closed containers in cool, dry places.
Avoid contact with eyes and ingestion.
Regulatory Status:
FDA-approved for use in hand sanitizers (≥ 60% IPA).
Listed in USP, EP, JP pharmacopeias for pharmaceutical grade.
Q1: Why is 70% isopropyl alcohol more effective than 99% for disinfection?
70% IPA penetrates cell walls more effectively and allows longer contact time, while 99% evaporates too quickly to kill all microbes.
Q2: Can isopropyl alcohol be used on electronics?
Yes. It evaporates quickly and leaves no residue, making it ideal for cleaning circuit boards, connectors, and glass screens.
Q3: Is IPA safe for skin?
In small amounts (as in sanitizers), yes. Prolonged exposure may cause dryness or irritation. Always moisturize after frequent use.
Q4: What’s the difference between isopropyl alcohol and ethanol?
Both are disinfectants. Ethanol is more effective against viruses like norovirus, while IPA is excellent against bacteria and lipid-enveloped viruses. IPA is often preferred for industrial cleaning.
Q5: Can IPA be mixed with water?
Yes, it is fully miscible with water, allowing preparation of different concentration solutions (commonly 70%).