Introduction
Nicotinamide, also known as niacinamide or vitamin B3, is a water-soluble vitamin that plays a vital role in maintaining healthy skin. It is recognized for its powerful anti-inflammatory, anti-aging, and barrier-repairing properties, making it a popular choice in modern cosmetic and dermatological formulations.
INCI Name: Niacinamide
Other Names: Nicotinamide, Vitamin B3
Molecular Formula: C₆H₆N₂O
Solubility: Freely soluble in water, alcohol
Appearance: White crystalline powder
Purity: ≥99%
Brightening Effect: Inhibits melanin production to even out skin tone
Barrier Repair: Strengthens the skin’s natural barrier and prevents water loss
Sebum Control: Helps regulate oil production, ideal for acne-prone skin
Anti-Inflammatory: Reduces redness, irritation, and sensitivity
Collagen Support: Stimulates dermal repair and smooths fine lines
Product Type | Use Level | Function |
---|---|---|
Facial serums, creams | 2–5% | Brightening, anti-aging |
Acne treatments | 4–10% | Oil control, inflammation reduction |
Lotions and body care | 1–3% | Moisture balance, texture smoothing |
Sun care & after-sun | 1–5% | Barrier repair, anti-irritation |
Haircare | 0.5–2% | Scalp calming, follicle energizing |
Recommended pH: 5.0–7.0
Solubility: Easily dissolves in water; add during cooling phase
Compatibility: Stable with many actives like hyaluronic acid, zinc, and panthenol
Storage: Cool, dry place in sealed packaging
✅ Multi-functional skincare active
✅ Suitable for all skin types, including sensitive
✅ Well-tolerated, minimal irritation risk
✅ Enhances performance of other ingredients
❌ Not stable in very acidic environments (<pH 4)
❌ High concentrations may cause flushing in some users
Q: Can nicotinamide be used daily?
A: Yes, it is suitable for everyday use and integrates well into both day and night skincare routines.
Q: Does it work with retinol or AHA/BHA acids?
A: It can be used with these actives, but pH balance should be considered to avoid irritation.
Q: Is it safe for sensitive or acne-prone skin?
A: Absolutely. It’s especially effective for reducing acne-related inflammation and regulating oil.
Nicotinamide is a powerhouse skincare ingredient valued for its versatility and effectiveness. Whether you're formulating for hydration, anti-aging, or acne treatment, this vitamin B3 derivative enhances skin health on multiple fronts—making it an essential component in cutting-edge cosmetic science.