Pentapeptide-3, also known as Vialox peptide, is a synthetic peptide developed to reduce dynamic wrinkles caused by facial expressions. Often compared to Botox for its mechanism of action, it relaxes facial muscles and smooths fine lines without injections, making it a popular ingredient in non-invasive anti-aging skincare products.
Name: Pentapeptide-3 (Vialox peptide)
Category: Synthetic cosmetic peptide
Appearance: White to off-white powder (formulated in serums and creams)
Solubility: Water-soluble
Stability: Stable under cosmetic formulation conditions
✨ Reduces expression lines around the eyes, forehead, and mouth
Non-invasive “Botox-like” alternative in topical skincare
Improves skin smoothness and texture
Works well in synergy with other anti-aging peptides
Gentle and safe for daily use
Industry | Function | Examples |
---|---|---|
Skincare & Cosmetics | Anti-wrinkle and smoothing agent | Eye creams, serums, anti-aging creams |
Dermatological Care | Non-invasive wrinkle reduction | Expression line-targeting products |
Luxury Beauty Products | Advanced peptide-based treatments | Premium lifting and firming formulas |
Mode of Action
Pentapeptide-3 works by modulating neurotransmitter release at the neuromuscular junction, which temporarily reduces muscle contractions responsible for expression lines. Over time, this relaxes dynamic wrinkles and leads to smoother skin without injections.
Non-invasive alternative to Botox
Safe for home use in daily skincare routines
Targets expression lines like crow’s feet and forehead wrinkles
Can be combined with retinol or hyaluronic acid for enhanced results
Works best on dynamic wrinkles, less on deep static wrinkles
Requires continuous use to maintain results
Visible results typically appear in 4–8 weeks
Q: How is Pentapeptide-3 different from Botox?
A: While Botox is an injectable neuromodulator, Pentapeptide-3 is a topical peptide that gently reduces muscle contractions without invasive procedures.
Q: Can it be used around the eyes?
A: Yes, it is safe for the delicate eye area and is often formulated in eye creams.
Q: Is it suitable for sensitive skin?
A: Yes, Pentapeptide-3 is well-tolerated and non-irritating for most skin types.
Pentapeptide-3 offers a non-invasive solution for expression lines, delivering smoother, younger-looking skin over time. Its Botox-like mechanism without injections makes it an attractive choice for those seeking advanced but gentle anti-aging care.